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This Trade Report explores the nature of the cosmetics & personal care sector in Africa specifically from the perspective of medium, small and micro enterprises (MSMEs), utilising a new set of primary field survey-collected data. This is done by firstly considering the background relating to value chains at the global and regional chains in general, the current, post Covid-19 context and importance in terms of the AfCFTA process. Thereafter the paper directly explores the data by profiling its dimensions and then analysing patterns of enterprise female ownership, trade relationships and trade direction, as well as patterns of self-reported value chain ‘position’ in terms of the most important dimensions in the data.